A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease

被引：268

作者：

Farlow, M

Anand, R

Messina, J

Hartman, R

Veach, J

机构：

[1] Indiana Univ, Sch Med, Dept Neurol, Indianapolis, IN 46202 USA

[2] Novartis Pharmaceut Corp, Dept Med Affairs CNS, E Hanover, NJ USA

[3] Novartis Pharmaceut Corp, Dept Stat, E Hanover, NJ USA

来源：

EUROPEAN NEUROLOGY | 2000年 / 44卷 / 04期

关键词：

cholinesterase inhibitor; rivastigmine; clinical trial; Alzheimer's disease;

D O I：

10.1159/000008243

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The efficacy of a centrally active cholinesterase inhibitor, rivastigmine tartrate (ENA 713; Exelon(R)), in patients with mild to moderately severe Alzheimer's disease was evaluated in a 26-week open-label extension of a 26-week, double-blind, placebo-controlled study. By 52 weeks, patients originally treated with 6-12 mg/day rivastigmine had significantly better cognitive function than patients originally treated with placebo. Copyright (C) 2000 S. Karger AG., Basel.

引用

页码：236 / 241

页数：6

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