The outcome of in vitro fertilization in advanced endometriosis with previous surgery: A case-controlled study

被引：63

作者：

Aboulghar, MA ^{[1
]}

Mansour, RT ^{[1
]}

Serour, GI ^{[1
]}

Ai-Inany, HG ^{[1
]}

Aboulghar, MM ^{[1
]}

机构：

[1] Egyptian IVF ET Ctr, Cairo, Egypt

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2003年 / 188卷 / 02期

关键词：

advanced endometriosis; in vitro fertilization; endometriosis surgery; pregnancy rate;

D O I：

10.1067/mob.2003.13

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: This study was undertaken to evaluate the outcome of in vitro fertilization (IVF) in patients with advanced pelvic endometriosis and previous surgical treatment. STUDY DESIGN: A case controlled study was performed. RESULTS: Patients with the diagnosis of stage IV endometriosis with previous surgical treatment were treated by IVF (group A = 85). An age-matched group of patients (group B = 177) with tubal factor infertility were treated with the same protocol of IVF. In group A, cycle cancellation because of poor response occurred in 29.7% compared with 1.1% in the control group (relative risk 26.03, 95% Cl 6.02-112.45). There were 13 (15.3%) clinical pregnancies per stimulated cycle in group A compared with 93 (52.5%) clinical pregnancies in the control group, P < .0001 (odds ratio 0.29, 95% Cl 0.15-0.55). CONCLUSION: The outcome of IVF in stage IV endometriosis with previous surgery was significantly lower compared with an age-matched group of tubal factor infertility.

引用

页码：371 / 375

页数：5

共 25 条

[1]

ADAMSON GD, 1994, AM J OBSTET GYNECOL, V171, P488

[2] Patients with stages III and IV endometriosis have a poorer outcome of in vitro fertilization-embryo transfer than patients with tubal infertility [J].