Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE

被引:172
作者
Safran, M [1 ]
Chalifa-Caspi, V
Shmueli, O
Olender, T
Lapidot, M
Rosen, N
Shmoish, M
Peter, Y
Glusman, G
Feldmesser, E
Adato, A
Peter, I
Khen, M
Atarot, T
Groner, Y
Lancet, D
机构
[1] Weizmann Inst Sci, Dept Biol Serv, Bioinformat Unit, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel
关键词
D O I
10.1093/nar/gkg050
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent enhancements and current research in the GeneCards (GC) (http://bioinfo.weizmann.ac.il/cards/) project are described, including the addition of gene expression profiles and integrated gene locations. Also highlighted are the contributions of specialized associated human gene-centric databases developed at the Weizmann Institute. These include the Unified Database (UDB) (http://bioinfo.weizmann.ac.il/udb) for human genome mapping, the human Chromosome 21 database at the Weizmann Insti-tute (CroW 21) (http://bioinfo.weizmann.ac.il/crow21), and the Human Olfactory Receptor Data Explora-torium (HORDE) (http://bioinfo.weizmann.ac.il/HORDE). The synergistic relationships amongst these efforts have positively impacted the quality, quantity and usefulness of the GeneCards gene compendium.
引用
收藏
页码:142 / 146
页数:5
相关论文
共 22 条
  • [1] CHALIFACASPI V, 1997, GENOME DIGEST, V4, P15
  • [2] Extending traditional query-based integration approaches for functional characterization of post-genomic data
    Eckman, BA
    Kosky, AS
    Laroco, LA
    [J]. BIOINFORMATICS, 2001, 17 (07) : 587 - 601
  • [3] euGenes: a eukaryote genome information system
    Gilbert, DG
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 145 - 148
  • [4] The olfactory receptor gene superfamily: data mining, classification, and nomenclature
    Glusman, G
    Bahar, A
    Sharon, D
    Pilpel, Y
    White, J
    Lancet, D
    [J]. MAMMALIAN GENOME, 2000, 11 (11) : 1016 - 1023
  • [5] The complete human olfactory subgenome
    Glusman, G
    Yanai, I
    Rubin, I
    Lancet, D
    [J]. GENOME RESEARCH, 2001, 11 (05) : 685 - 702
  • [6] GESTALT: a workbench for automatic integration and visualization of large-scale genomic sequence analyses
    Glusman, G
    Lancet, DO
    [J]. BIOINFORMATICS, 2000, 16 (05) : 482 - 483
  • [7] The DNA sequence of human chromosome 21
    Hattori, M
    Fujiyama, A
    Taylor, TD
    Watanabe, H
    Yada, T
    Park, HS
    Toyoda, A
    Ishii, K
    Totoki, Y
    Choi, DK
    Soeda, E
    Ohki, M
    Takagi, T
    Sakaki, Y
    Taudien, S
    Blechschmidt, K
    Polley, A
    Menzel, U
    Delabar, J
    Kumpf, K
    Lehmann, R
    Patterson, D
    Reichwald, K
    Rump, A
    Schillhabel, M
    Schudy, A
    Zimmermann, W
    Rosenthal, A
    Kudoh, J
    Shibuya, K
    Kawasaki, K
    Asakawa, S
    Shintani, A
    Sasaki, T
    Nagamine, K
    Mitsuyama, S
    Antonarakis, SE
    Minoshima, S
    Shimizu, N
    Nordsiek, G
    Hornischer, K
    Brandt, P
    Scharfe, M
    Schön, O
    Desario, A
    Reichelt, J
    Kauer, G
    Blöcker, H
    Ramser, J
    Beck, A
    [J]. NATURE, 2000, 405 (6784) : 311 - 319
  • [8] Higgins DG, 1996, METHOD ENZYMOL, V266, P383
  • [9] The Ensembl genome database project
    Hubbard, T
    Barker, D
    Birney, E
    Cameron, G
    Chen, Y
    Clark, L
    Cox, T
    Cuff, J
    Curwen, V
    Down, T
    Durbin, R
    Eyras, E
    Gilbert, J
    Hammond, M
    Huminiecki, L
    Kasprzyk, A
    Lehvaslaiho, H
    Lijnzaad, P
    Melsopp, C
    Mongin, E
    Pettett, R
    Pocock, M
    Potter, S
    Rust, A
    Schmidt, E
    Searle, S
    Slater, G
    Smith, J
    Spooner, W
    Stabenau, A
    Stalker, J
    Stupka, E
    Ureta-Vidal, A
    Vastrik, I
    Clamp, M
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 38 - 41
  • [10] Kent WJ, 2002, GENOME RES, V12, P656, DOI [10.1101/gr.229202, 10.1101/gr.229202. Article published online before March 2002]