Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?

被引：2

作者：

Van den Berghe, Greet ^{[1
]}

机构：

[1] Catholic Univ Louvain, Dept Intens Care Med, B-3000 Louvain, Belgium

来源：

CRITICAL CARE | 2010年 / 14卷 / 01期

关键词：

CRITICALLY-ILL PATIENTS; INTENSIVE INSULIN; THERAPY; HYPERINSULINEMIA; INFLAMMATION;

D O I：

10.1186/cc8228

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A small study in patients with severe sepsis suggested that insulin infused to normalize blood glucose levels increased forearm flow. This clinical observation supports the effect of insulin on the endothelium, as previously shown by in vitro studies and by in vivo animal models of critical illness, but the clinical consequences remain unclear.

引用

页数：2