The diet of adult and juvenile Weddell seals (Leptonychotes weddellii) in McMurdo Sound, Antarctica, was determined from both seat and stable isotope analyses, to ascertain if foraging behavior varied with age, season, or diving pattern. Seats were collected over 6 years and recovered hard parts identified. Stable carbon and nitrogen isotope values were determined for seal blood samples and potential prey items and used to identify primary prey species and assess trophic interactions. Pleuragramma antarcticum remains were recovered from between 70 and 100% of the seats, and there was little evidence for inter-annual or age-specific variation in foraging behavior. However, stable isotope and dive data analyses indicated that while most seals foraged predominantly on pelagic fish and squid, some juveniles concentrated on shallow benthic Trematomus spp. Combining these three methods permitted him conclusions about diet and foraging behavior to be drawn.