Pyrrolizidine alkaloids from Onosma arenaria (Boraginaceae)

被引：40

作者：

El-Shazly, A

Abdel-Ghani, A

Wink, M ^{[1
]}

机构：

[1] Univ Heidelberg, Inst Pharmazeut Biol, INF 364, D-69120 Heidelberg, Germany

[2] Zagazig Univ, Fac Pharm, Dept Pharmacognosy, Zagazig, Egypt

来源：

BIOCHEMICAL SYSTEMATICS AND ECOLOGY | 2003年 / 31卷 / 05期

关键词：

Onosma arenaria; Boraginaceae; pyrrolizidine alkaloids; uplandicine; NMR; gas liquid chromatography (GLC); GLC-mass spectrometry;

D O I：

10.1016/S0305-1978(02)00177-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Uplandicine, a 1,2-unsaturated pyrrolizidine alkaloid esterified with acetyl and echimidinyl moieties at C-7 and C-9, respectively, was isolated as a major component from the alkaloid extract of Onosma arenaria. Its structure was confirmed by MS (EI and positive FAB), 1H- and 13C-NMR analysis. Furthermore, nine minor alkaloids were identified on the basis of mass spectral data and/or Kovats retention indices. (C) 2003 Published by Elsevier Science Ltd.

引用

页码：477 / 485

页数：9

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