Water-accelerated aldol reaction of ketene silyl acetals with carbonyl compounds

被引：42

作者：

Loh, TP ^{[1
]}

Feng, LC ^{[1
]}

Wei, LL ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

来源：

TETRAHEDRON | 2000年 / 56卷 / 37期

关键词：

water-accelerated aldol reaction; ketene silyl acetal; carbonyl compounds;

D O I：

10.1016/S0040-4020(00)00630-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The aldol reactions of ketene silyl acetals with reactive aldehydes proceed smoothly in water to afford the corresponding aldol products in good yields. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7309 / 7312

页数：4

共 10 条

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[5] Novel one-pot mannich-type reaction in water:: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters
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Wei, LL
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[8] LUBINEAU A, 1994, SYNTHESIS-STUTTGART, P741
[9] UNIQUE CATALYSIS BY EU(DPPM)3 - CATALYTIC MOLECULAR RECOGNITION IN ALDOL AND MICHAEL REACTIONS
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[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (18) : 5456 - 5459
[10] NEW CROSS-ALDOL REACTIONS - REACTIONS OF SILYL ENOL ETHERS WITH CARBONYL-COMPOUNDS ACTIVATED BY TITANIUM TETRACHLORIDE
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (24) : 7503 - 7509

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