Novel one-pot mannich-type reaction in water:: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

被引：154

作者：

Loh, TP ^{[1
]}

Wei, LL ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 3-4期

关键词：

D O I：

10.1016/S0040-4039(97)10478-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give beta-amino ketones and esters in moderate to good yields. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：323 / 326

页数：4

共 18 条

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[6] Indium-trichloride catalyzed Mukaiyama-aldol reaction in water: Solubility, aggregation and internal pressure effect
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[7] Loh TP, 1997, TETRAHEDRON LETT, V38, P3993
[8] A highly stereoselective synthesis of beta-trifluoromethylated homoallylic alcohols in water
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[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (09): : 980 - 982
[9] LOH TP, 1996, J CHEM SOC CHEM COMM, P1929
[10] LOH TP, 1996, J CHEM SOC CHEM COMM, P1819

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