Novel one-pot mannich-type reaction in water:: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

被引:154
作者
Loh, TP [1 ]
Wei, LL [1 ]
机构
[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore
关键词
D O I
10.1016/S0040-4039(97)10478-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give beta-amino ketones and esters in moderate to good yields. (C) 1997 Elsevier Science Ltd. All rights reserved.
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页码:323 / 326
页数:4
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