Novel one-pot mannich-type reaction in water:: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

被引：154

作者：

Loh, TP ^{[1
]}

Wei, LL ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 3-4期

关键词：

D O I：

10.1016/S0040-4039(97)10478-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give beta-amino ketones and esters in moderate to good yields. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：323 / 326

页数：4

共 18 条

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[16] OJIMA I, 1977, TETRAHEDRON LETT, P3643
[17] ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS .1. THE REACTION OF DIMETHYLKETENE SILYL ACETAL WITH (S)-ALKYLIDENE(1-ARYLETHYL)AMINES PROMOTED BY TITANIUM TETRACHLORIDE
OJIMA, I
INABA, S
[J]. TETRAHEDRON LETTERS, 1980, 21 (21) : 2077 - 2080
[18] ONAKA M, 1993, SYNLETT, P141

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