Novel bis-N-[2-(diphenylphosphino)ferrocenylcarbonyl]diaminocyclohexane ligands:: application in asymmetric allylic alkylation of imino esters with simple allyl carbonate

被引：118

作者：

You, SL ^{[1
]}

Hou, XL ^{[1
]}

Dai, LX ^{[1
]}

Cao, BX ^{[1
]}

Sun, J ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 19期

关键词：

D O I：

10.1039/b003804k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Several derivatives of ferrocene ligands with planar chirality were investigated in palladium-catalysed asymmetric allylic alkylation of iminoesters, in which bis-ferrocene ligand 7 containing a chiral pocket showed good enantiocontrol in this reaction; the products having a quaternary chiral center were obtained with up to 75.3% ee.

引用

页码：1933 / 1934

页数：2

共 25 条

[21] Catalytic asymmetric alkylation of nucleophiles:: Asymmetric synthesis of α-alkylated amino acids [J].

Trost, BM ;

Ariza, X .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1997, 36 (23) :2635-2637

[22] ASYMMETRIC TOTAL SYNTHESIS OF DIBENZOCYCLOOCTADIENE LIGNANS (-)-SCHIZANDRIN AND (-)-ISOSCHIZANDRIN - STRUCTURE REVISION OF (+)-ISOSCHIZANDRIN [J].

WARSHAWSKY, AM ;

MEYERS, AI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (22) :8090-8099

[23]

WILLIAMS RM, 1989, SYNTHEISS OPTICALLY, V7

[24] New strategies to alpha-alkylated alpha-amino acids [J].

Wirth, T .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1997, 36 (03) :225-227

[25] Enantioselective palladium catalyzed allylic substitution with chiral thioether derivatives of ferrocenyl-oxazoline and the role of planar chirality in this reaction [J].

You, SL ;

Zhou, YG ;

Hou, XL ;

Dai, LX .

CHEMICAL COMMUNICATIONS, 1998, (24) :2765-2766

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