The changing face of rheumatoid arthritis: sustained remission for all?

被引：66

作者：

Isaacs, John D. ^{[1
]}

机构：

[1] Newcastle Univ, Sch Med, Inst Cellular Med, Musculoskeletal Res Grp, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

来源：

NATURE REVIEWS IMMUNOLOGY | 2010年 / 10卷 / 08期

关键词：

PLACEBO-CONTROLLED TRIAL; DISEASE-ACTIVITY SCORE; RANDOMIZED-TRIAL; DOUBLE-BLIND; COMBINATION THERAPY; BLOOD-DONORS; TREATMENT STRATEGIES; PROSPECTIVE COHORT; LONG-TERM; T-CELLS;

D O I：

10.1038/nri2804

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Earlier diagnosis and treatment, plus biological therapies, have transformed the outlook for many patients with rheumatoid arthritis. In the future, new biomarkers for diagnosis, prognosis and therapeutic response will further improve outcomes. Additionally, preclinical diagnosis and tolerogenic therapies could provide sustained remission for some individuals, although ethical and societal challenges must also be addressed before rheumatoid arthritis becomes 'yesterday's disease'.

引用

收藏

页码：605 / 611

页数：7

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