Preservation of integron types among Enterobacteriaceae producing extended-spectrum β-lactamases in a Spanish hospital over a 15-year period (1988 to 2003)

被引:41
作者
Machado, Elisabete
Ferreira, Joana
Novais, Angela
Peixe, Luisa
Canton, Rafael
Baquero, Fernando
Coque, Teresa M.
机构
[1] Hosp Univ Ramon y Cajal, Microbiol Serv, IMSALUD, E-28034 Madrid, Spain
[2] CSIC, Unidad Resistencia Antibiot & Virulencia Bacteria, Madrid 6, Spain
[3] Univ Porto, Fac Farm, REQUIMTE, P-4100 Oporto, Portugal
[4] Univ Fernando Pessoa, Fac Ciencias Saude, Oporto, Portugal
关键词
D O I
10.1128/AAC.01389-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The variable presence of integrons among extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae species (0 to 66%) is described. Association between bla(ESBL) and integrons occurred when these are linked to specific ESBL-type genes (In60 bearing ISCR1 and bla(CTX-M-9)) or when ESBL genes were superimposed onto selected plasmids carrying integrons. Some integrons were identical to those found during decades worldwide, illustrating the preservation of the genetic elements carrying them.
引用
收藏
页码:2201 / 2204
页数:4
相关论文
共 42 条
[1]  
[Anonymous], 2006, J ANTIMICROB CHEMOTH, DOI DOI 10.1093/jac/dki412
[2]   Dissemination amongst humans and food products of animal origin of a Salmonella typhimurium clone expressing an integron-borne OXA-30 β-lactamase [J].
Antunes, P ;
Machado, J ;
Sousa, JC ;
Peixe, L .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 54 (02) :429-434
[3]   Diverse class 2 integrons in bacteria from beef cattle sources [J].
Barlow, Robert S. ;
Gobius, Kari S. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 58 (06) :1133-1138
[4]   Integrons in Escherichia coli from food-producing animals in the Netherlands [J].
Box, ATA ;
Mevius, DJ ;
Schellen, P ;
Verhoef, J ;
Fluit, AC .
MICROBIAL DRUG RESISTANCE, 2005, 11 (01) :53-57
[5]   Epidemiology of extended-spectrum β-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year period [J].
Cantón, R ;
Oliver, A ;
Coque, TM ;
Varela, MD ;
Pérez-Díaz, JC ;
Baquero, F .
JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (04) :1237-1243
[6]   Genes encoding TEM-4, SHV-2, and CTX-M-10 extended-spectrum β-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital (Madrid, 1989 to 2000) [J].
Coque, TM ;
Oliver, A ;
Pérez-Díaz, C ;
Baquero, F ;
Cantón, R .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (02) :500-510
[7]   High prevalence of the plasmid-mediated quinolone resistance determinant qnrA in multidrug-resistant Enterobacteriaceae from blood cultures in Liverpool, UK [J].
Corkill, JE ;
Anson, JJ ;
Hart, CA .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (06) :1115-1117
[8]   Molecular characterization of a new class 3 integron in Klebsiella pneumoniae [J].
Correia, M ;
Boavida, F ;
Grosso, F ;
Salgado, MJ ;
Lito, LM ;
Cristino, JM ;
Mendo, S ;
Duarte, A .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (09) :2838-2843
[9]   Antimicrobial resistance and genetic diversity of Shigella sonnei isolates from Western Ireland, an area of low incidence of infection [J].
DeLappe, N ;
O'Halloran, F ;
Fanning, S ;
Corbett-Feeney, G ;
Cheasty, T ;
Cormican, M .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (05) :1919-1924
[10]  
DUBOIS V, 2007, ANTIMICROB AGENTS CH