Preservation of integron types among Enterobacteriaceae producing extended-spectrum β-lactamases in a Spanish hospital over a 15-year period (1988 to 2003)

被引:41
作者
Machado, Elisabete
Ferreira, Joana
Novais, Angela
Peixe, Luisa
Canton, Rafael
Baquero, Fernando
Coque, Teresa M.
机构
[1] Hosp Univ Ramon y Cajal, Microbiol Serv, IMSALUD, E-28034 Madrid, Spain
[2] CSIC, Unidad Resistencia Antibiot & Virulencia Bacteria, Madrid 6, Spain
[3] Univ Porto, Fac Farm, REQUIMTE, P-4100 Oporto, Portugal
[4] Univ Fernando Pessoa, Fac Ciencias Saude, Oporto, Portugal
关键词
D O I
10.1128/AAC.01389-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The variable presence of integrons among extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae species (0 to 66%) is described. Association between bla(ESBL) and integrons occurred when these are linked to specific ESBL-type genes (In60 bearing ISCR1 and bla(CTX-M-9)) or when ESBL genes were superimposed onto selected plasmids carrying integrons. Some integrons were identical to those found during decades worldwide, illustrating the preservation of the genetic elements carrying them.
引用
收藏
页码:2201 / 2204
页数:4
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