Digestion and Absorption of Siraitia grosvenori Triterpenoids in the Rat

被引:74
作者
Murata, Yuji [1 ,2 ]
Ogawa, Takahisa [2 ]
Suzuki, Yasushi A. [2 ]
Yoshikawa, Shinichi [2 ]
Inui, Hiroshi [1 ,3 ]
Sugiura, Masaki [2 ]
Nakano, Yoshihisa [1 ]
机构
[1] Osaka Prefecture Univ, Grad Sch Life & Environm Sci, Dept Appl Biol Chem, Osaka 5998531, Japan
[2] Saraya Co Ltd, Biochem Lab, Osaka 5820028, Japan
[3] Osaka Prefecture Univ, Ctr Res & Dev Bioresources, Osaka 5998570, Japan
关键词
Siraitia grosvenori Swingle; mogroside V; glycoside; aglycone; conjugate; CUCURBITANE-GLYCOSIDES; UNRIPE FRUITS;
D O I
10.1271/bbb.90832
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
When administered to rats, mogroside V (a penta-glucose-conjugated mogroside), the main sweetening component of Siraitia grosvenori, was mostly degraded by digestive enzymes and intestinal microflora, and was excreted in the feces as mogrol (aglycone) and its mono- and diglucosides. However, trace amounts of mogrol and its monoglucoside were found in the portal blood as sulfates and/or glucuronide conjugates.
引用
收藏
页码:673 / 676
页数:4
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