Bringing efficiency to materials synthesis: The philosophy of click chemistry

被引:150
作者
Hawker, Craig J. [1 ]
Fokin, Valery V.
Finn, M. G.
Sharpless, K. Barry
机构
[1] Univ Calif Santa Barbara, Mat Res Lab, Santa Barbara, CA 93106 USA
[2] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[3] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
基金
美国国家科学基金会;
关键词
D O I
10.1071/CH07107
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Click chemistry is considered as one of the most rapidly growing areas of research in materials synthesis. Click chemistry can be applied to highly efficient dendritic materials synthesis requiring minimal purification and in the development of novel adhesives for copper surfaces. Click chemistry allows particular new materials to be prepared and opens up whole new avenues for materials to be prepared more efficiently. It also allows existing materials classes to be prepared with unprecedented efficiency and versatility opening up an array of new structures. It provides a valuable alternative to living polymerization methods such as anionic, ring opening, living radical systems where blocks are made through sequential polymerization of monomers rather than through coupling of performed blocks. It is expected that the efficiency and user friendliness of click reactions will continue to allow new functional materials with important commercial applications to be prepared.
引用
收藏
页码:381 / 383
页数:3
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