Optical projection tomography

被引:128
作者
Sharpe, J [1 ]
机构
[1] Western Gen Hosp, MRC Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland
关键词
3-D imaging; reconstruction; gene expression; fluorescence; phenotyping;
D O I
10.1146/annurev.bioeng.6.040803.140210
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Optical projection tomography is anew approach for three-dimensional (3-D) imaging of small biological specimens. It fills an imaging gap between MRI and confocal microscopy, being most suited to specimens that are from 1 to 10 mm across. The tomographic principles of optical projection tomography (OPT) are explained, its most important applications in biomedical research explored, and comparisons drawn of its pros and cons compared to a number of alternative imaging technologies.
引用
收藏
页码:209 / 228
页数:24
相关论文
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