Optical projection tomography

被引：128

作者：

Sharpe, J ^{[1
]}

机构：

[1] Western Gen Hosp, MRC Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING | 2004年 / 6卷

关键词：

3-D imaging; reconstruction; gene expression; fluorescence; phenotyping;

D O I：

10.1146/annurev.bioeng.6.040803.140210

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Optical projection tomography is anew approach for three-dimensional (3-D) imaging of small biological specimens. It fills an imaging gap between MRI and confocal microscopy, being most suited to specimens that are from 1 to 10 mm across. The tomographic principles of optical projection tomography (OPT) are explained, its most important applications in biomedical research explored, and comparisons drawn of its pros and cons compared to a number of alternative imaging technologies.

引用

页码：209 / 228

页数：24

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