The Use of Systemic Hypothermia for the Treatment of an Acute Cervical Spinal Cord Injury in a Professional Football Player

被引:55
作者
Cappuccino, Andrew [1 ,2 ]
Bisson, Leslie J. [2 ,3 ,4 ]
Carpenter, Bud [2 ]
Marzo, John [2 ,3 ]
Dietrich, W. Dalton, III [5 ]
Cappuccino, Helen [6 ]
机构
[1] Buffalo Spine Surg, Lockport, NY USA
[2] Team Orthoped Surgeon Buffalo Bills, Buffalo, NY USA
[3] SUNY Buffalo, Dept Orthoped, Buffalo, NY 14260 USA
[4] Team Buffalo Sabres, Buffalo, NY USA
[5] Univ Miami, Miller Sch Med, Dept Neurol Surg, Miami Project Cure Paralysis, Miami, FL 33136 USA
[6] SUNY Buffalo, Roswell Pk Canc Inst, Sch Med & Biomed Sci, Buffalo, NY 14260 USA
关键词
spinal cord injuries; hypothermia; cervical; football; TRAUMATIC BRAIN-INJURY; COMPRESSION INJURY; BLOOD-FLOW; MILD HYPOTHERMIA; RAT; DAMAGE; PATHOPHYSIOLOGY; TEMPERATURE; PROTECTION; RELEASE;
D O I
10.1097/BRS.0b013e3181b9dc28
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Design. Case Report. Objective. We will describe the injury and clinical course of an NFL Football player who sustained a complete spinal cord injury and was treated with conventional care in addition to modest systemic hypothermia. Summary of Background Data. Systemically induced moderate hypothermia is a potentially neuroprotective intervention in acute spinal cord injury. However, case descriptions of human patients receiving systemic hypothermia after spinal cord injuries are lacking in the literature. Methods. Here, we present the case of a National Football League player who sustained a complete (ASIA A) spinal cord injury from a C3/4 fracture dislocation. Moderate systemic hypothermia was instituted immediately after his injury, in addition to standard medical/surgical treatment, including, surgical decompression and intravenous methylprednisolone. Results. The patient experienced significant and rapid neurologic improvement, and within weeks of his injury was walking with harness assistance. Since that time, the patient has continued to make significant progress in his rehabilitation (now ASIA D). Conclusion. The extent to which this hypothermia contributed to his neurologic recovery is difficult to determine. It is hoped that this case will draw attention to the need for further preclinical and clinical studies to elucidate the role of hypothermia in acute spinal cord injury. Until these studies are completed, it is impossible to advocate for systemic hypothermia as a standard of care.
引用
收藏
页码:E57 / E62
页数:6
相关论文
共 72 条
  • [1] Technical refinements and drawbacks of a surface cooling technique for the treatment of severe acute ischemic stroke
    Abou-Chebl, A
    DeGeorgia, MA
    Andrefsky, JC
    Krieger, DW
    [J]. NEUROCRITICAL CARE, 2004, 1 (02) : 131 - 143
  • [2] Guidelines for the Early Management of Patients With Ischemic Stroke - 2005 guidelines update - A scientific statement from the Stroke Council of the American Heart Association/American Stroke Association
    Adams, H
    Adams, R
    Del Zoppo, G
    Goldstein, LB
    [J]. STROKE, 2005, 36 (04) : 916 - 923
  • [3] ALAN S, 2008, NY TIMES 0115
  • [4] SPINAL-CORD ISCHEMIA AND REPERFUSION METABOLISM - THE EFFECT OF HYPOTHERMIA
    ALLEN, BT
    DAVIS, CG
    OSBORNE, D
    KARL, I
    [J]. JOURNAL OF VASCULAR SURGERY, 1994, 19 (02) : 332 - 340
  • [5] ALLEN BT, 1996, J VASC SURG, V19, P339
  • [6] PATHOPHYSIOLOGY OF SPINAL-CORD TRAUMA
    ANDERSON, DK
    HALL, ED
    [J]. ANNALS OF EMERGENCY MEDICINE, 1993, 22 (06) : 987 - 992
  • [7] Therapeutic Hypothermia
    Arrica, Mauro
    Bissonnette, Bruno
    [J]. SEMINARS IN CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2007, 11 (01) : 6 - 15
  • [8] Hypothermia: Evaluation, electrocardiographic manifestations, and management
    Aslam, AF
    Aslam, AK
    Vasavada, BC
    Khan, IA
    [J]. AMERICAN JOURNAL OF MEDICINE, 2006, 119 (04) : 297 - 301
  • [9] Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia
    Bernard, SA
    Gray, TW
    Buist, MD
    Jones, BM
    Silvester, W
    Gutteridge, G
    Smith, K
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (08) : 557 - 563
  • [10] Targeting the host inflammatory response in traumatic spinal cord injury
    Bethea, JR
    Dietrich, WD
    [J]. CURRENT OPINION IN NEUROLOGY, 2002, 15 (03) : 355 - 360