Dysphonia associated with inhaled steroids

被引:50
作者
Lavy, JA
Wood, G
Rubin, JS
Harries, M
机构
[1] Royal Natl Throat Nose & Ear Hosp, London WC1X 8DA, England
[2] Royal Sussex Cty Hosp, Brighton BN2 5BE, E Sussex, England
关键词
asthma; voice; dysphonia; videostroboscopy;
D O I
10.1016/S0892-1997(00)80014-4
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
The use of inhaled steroids in the treatment of asthma is not without its complications. In some studies up to 50% of such patients complain of oropharyngeal and voice problems. We present the findings in 22 patients complaining of dysphonia who underwent videostrobolaryngoscopy (VSL) and computerized speech analysis. A number of abnormalities were identified. On VSL, these included mucosal changes (noted in 58%), apposition abnormalities (noted in 43%), and supraglottic hyperfunction (noted in 40%). On speech analysis, cycle-to-cycle irregularity was frequently noted (mean of 39%). Maximum phonation time was reduced in 73%. Our findings did not confirm the widely held views that steroid dysphonia is due primarily to a fungal infection or a steroid-induced adductor myasthenia of the larynx. A larger-scale prospective study is indicated.
引用
收藏
页码:581 / 588
页数:8
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