Spatially deconvolved optical coherence tomography

被引：87

作者：

Woolliams, Peter D. ^{[1
]}

Ferguson, Robert A. ^{[1
]}

Hart, Christian ^{[1
]}

Grimwood, Alex ^{[2
]}

Tomlins, Peter H. ^{[1
]}

机构：

[1] Natl Phys Lab, Biophoton Grp, Teddington TW11 0LW, Middx, England

[2] Royal Inst Great Britain, London W1S 4BS, England

来源：

APPLIED OPTICS | 2010年 / 49卷 / 11期

关键词：

RESOLUTION; SCATTERING; TISSUE;

D O I：

10.1364/AO.49.002014

中图分类号：

O43 [光学];

学科分类号：

070207 [光学];

摘要：

In this paper we present spatially mapped point-spread function (PSF) measurements of an optical coherence tomography (OCT) instrument and subsequent spatial deconvolution. The OCT B-scan image plane was divided into 2400 subimages, for which PSFs were determined from OCT measurements of a specially designed phantom. Each PSF was deconvolved from its corresponding subimage of the phantom using the Lucy-Richardson algorithm. Following deconvolution, all of the subimages were reassembled to form a final deconvolved image, from which the resolution improvement was quantitatively assessed. The lateral resolution was found to improve by 3:1 mu m compared to an axial resolution enhancement of 4.5 mu m. The spatial uniformity of both axial and lateral resolution was also observed to increase following deconvolution, demonstrating the advantage of deconvolving local PSFs from their associated subimages. (C) 2010 Optical Society of America

引用

页码：2014 / 2021

页数：8

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