Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopy

被引：494

作者：

Weiss, S ^{[1
]}

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley, CA 94720 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2000年 / 7卷 / 09期

关键词：

D O I：

10.1038/78941

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dynamic structural changes of macromolecules undergoing biochemical reactions can be studied using novel single molecule spectroscopy tools. Recent advances applying such distance and orientation molecular rulers to biological systems are reviewed, and future prospects and challenges are discussed.

引用

页码：724 / 729

页数：6

共 52 条

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