Eupergit® C, a carrier for immobilization of enzymes of industrial potential

被引：356

作者：

Katchalski-Katzir, E

Kraemer, DM

机构：

[1] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel

[2] Rohm GmbH, Darmstadt, Germany

来源：

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 2000年 / 10卷 / 1-3期

关键词：

Eupergit (R) C; other carriers; immobilized enzymes; biocatalysts; operational stability; automatic reactor; simulation; industrial performance;

D O I：

10.1016/S1381-1177(00)00124-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eupergit(R) C is a carrier consisting of macroporous beads for immobilizing enzymes of industrial potential for the production of fine chemicals and pharmaceuticals. Various enzymes immobilized on Eupergit(R) C are reviewed in comparison with other carrier materials in terms of the operational stability of the respective biocatalysts at substrate concentrations realistic for industrial production. Other aspects of relevance in that field, such as the demand for purity of enzyme to be immobilized or type of reactor optimal for a given application, are also discussed. An automatic reactor simulating, at laboratory scale, the performance of an industrial stirred tank reactor (STR) is described, and its utilization for evaluating the performance of immobilized enzymes is shown. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：157 / 176

页数：20

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