Chaperonins

被引：35

作者：

Braig, K ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 02期

关键词：

D O I：

10.1016/S0959-440X(98)80033-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular chaperones are essential to all living organisms. Their key role consists of mediating protein folding within the cell. Recent functional studies have provided more detailed information about the function and regulation of the chaperone network. Highlights of the past year include the crystal structure determinations of the asymmetric GroEL-GroES complex and of their isolated peptide-binding domains.

引用

页码：159 / 165

页数：7

共 56 条

[21] Native-like structure of a protein-folding intermediate bound to the chaperonin GroEL
Goldberg, MS
Zhang, J
Sondek, S
Matthews, CR
Fox, RO
Horwich, AL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (04) : 1080 - 1085
[22] COOPERATION OF GROEL/GROES AND DNAK/DNAJ HEAT-SHOCK PROTEINS IN PREVENTING PROTEIN MISFOLDING IN ESCHERICHIA-COLI
GRAGEROV, A
NUDLER, E
KOMISSAROVA, N
GAITANARIS, GA
GOTTESMAN, ME
NIKIFOROV, V
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (21) : 10341 - 10344
[23] Significant hydrogen exchange protection in GroEL-bound DHFR is maintained during iterative rounds of substrate cycling
Gross, M
Robinson, CV
Mayhew, M
Hartl, FU
Radford, SE
[J]. PROTEIN SCIENCE, 1996, 5 (12) : 2506 - 2513
[24] Molecular chaperones in cellular protein folding
Hartl, FU
[J]. NATURE, 1996, 381 (6583) : 571 - 580
[25] Escherichia coli trigger factor is a prolyl isomerase that associates with nascent polypeptide chains
Hesterkamp, T
Hauser, S
Lutcke, H
Bukau, B
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (09) : 4437 - 4441
[26] The crystal structure of the GroES co-chaperonin at 2.8 angstrom resolution
Hunt, JF
Weaver, AJ
Landry, SJ
Gierasch, L
Deisenhofer, J
[J]. NATURE, 1996, 379 (6560) : 37 - 45
[27] BINDING AND HYDROLYSIS OF NUCLEOTIDES IN THE CHAPERONIN CATALYTIC CYCLE - IMPLICATIONS FOR THE MECHANISM OF ASSISTED PROTEIN FOLDING
JACKSON, GS
STANIFORTH, RA
HALSALL, DJ
ATKINSON, T
HOLBROOK, JJ
CLARKE, AR
BURSTON, SG
[J]. BIOCHEMISTRY, 1993, 32 (10) : 2554 - 2563
[28] KNAPP S, 1994, J MOL BIOL, V242, P397
[29] KUBOTA H, 1995, EUR J BIOCHEM, V230, P3, DOI 10.1111/j.1432-1033.1995.0003i.x
[30] IDENTIFICATION OF 6 TCP-1-RELATED GENES ENCODING DIVERGENT SUBUNITS OF THE TCP-1-CONTAINING CHAPERONIN
KUBOTA, H
HYNES, G
CARNE, A
ASHWORTH, A
WILLISON, K
[J]. CURRENT BIOLOGY, 1994, 4 (02) : 89 - 99

← 1 2 3 4 5 6 →