TRPs as mechanosensitive channels

被引：31

作者：

Barritt, G

Rychkov, G

机构：

[1] Flinders Univ S Australia, Sch Med, Fac Hlth Sci, Dept Med Biochem, Adelaide, SA 5001, Australia

[2] Univ Adelaide, Sch Mol & Biomed Sci, Dept Physiol, Adelaide, SA 5005, Australia

来源：

NATURE CELL BIOLOGY | 2005年 / 7卷 / 02期

关键词：

D O I：

10.1038/ncb0205-105

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mechanosensitive channels are essential for effective cellular function, but elucidation of their molecular identity and mechanisms of activation has proven difficult. Two recent studies now implicate members of the transient receptor potential (TRP) family as components of the mechanosensitive channels in vertebrate hair cells (TRPA1) and stretch-activated channels (TRPC1) in several different vertebrate cell types.

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页码：105 / 107

页数：3

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