Thrombotic Microangiopathies: Multimers, Metalloprotease, and Beyond

被引：18

作者：

Moake, Joel ^{[1
]}

机构：

[1] Rice Univ, Houston, TX 77251 USA

来源：

CTS-CLINICAL AND TRANSLATIONAL SCIENCE | 2009年 / 2卷 / 05期

关键词：

TTP; HUS; other thrombotic microangiopathies; VON-WILLEBRAND-FACTOR; FACTOR-CLEAVING PROTEASE; HEMOLYTIC-UREMIC SYNDROME; FACTOR-H-AUTOANTIBODIES; VONWILLEBRAND-FACTOR MULTIMERS; PLATELET GLYCOPROTEIN-IB; THROMBOCYTOPENIC PURPURA; ENDOTHELIAL-CELLS; AURINTRICARBOXYLIC ACID; DEFICIENT ACTIVITY;

D O I：

10.1111/j.1752-8062.2009.00142.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The pathophysiology of various types of thrombotic microangiopathies is coming progressively into focus. Therapeutic advances are likely to follow at a quickening pace. This discussion focuses on thrombotic thrombocytopenic purpura (TTP), the hemolytic-uremic syndrome (HUS), thrombotic microangiopathies associated with transplantation-immunosuppression or anti-angiogenesis therapy, and the preeclampsia/hemolysis-elevated liver enzymes and low platelets syndrome (HELLP).

引用

收藏

页码：366 / 373

页数：8

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