Efficient synthesis of triazoles from D-arabinose and L-fucose

被引：20

作者：

Flessner, T

Wong, CH

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 41期

基金：

美国国家卫生研究院;

关键词：

carbohydrates; iminosugars; triazoles;

D O I：

10.1016/S0040-4039(00)01356-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The efficient synthesis of sugar-derived triazoles via a one-pot substitution-cyclization-oxidation procedure is presented. Starting from D-arabinose and L-fucose, triazole structures as potential enzyme inhibitors were obtained in six to eight steps. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：7805 / 7808

页数：4

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