Eosinophilic lung disease induced by bicalutamide - A case report and review of the medical literature

被引：7

作者：

Wong, PW ^{[1
]}

Macris, N ^{[1
]}

DiFabrizio, L ^{[1
]}

Seriff, NS ^{[1
]}

机构：

[1] Lenox Hill Hosp, Dept Med, New York, NY 10021 USA

来源：

CHEST | 1998年 / 113卷 / 02期

关键词：

antiandrogen agent; drug-induced eosinophilic lung disease; pulmonary infiltrates and eosinophilia (PIE);

D O I：

10.1378/chest.113.2.548

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 69-year-old man with advanced prostate cancer was receiving antiandrogen therapy (bicalutamide [Casodex]). He developed dyspnea, peripheral eosinophilia and bilateral pulmonary interstitial infiltrates. Transbronchial biopsy confirmed pulmonary eosinophilia. Withdrawal of bicalutamide and initiation of steriod therapy resulted in clinical improvement.

引用

页码：548 / 550

页数：3

共 6 条

[1]

Blackledge GRP, 1996, EUR UROL, V29, P96

[2] The preclinical development of bicalutamide: Pharmacodynamics and mechanism of action [J].