First autopsy study of an Okinawan centenarian: Absence of many age-related diseases

被引：32

作者：

Bernstein, AM

Willcox, BJ

Tamaki, H

Kunishima, N

Suzuki, M

Willcox, DC

Yoo, JSK

Perls, TT

机构：

[1] Pacific Hlth Res Inst, Honolulu, HI 96813 USA

[2] Univ Hawaii, John A Burns Sch Med, Dept Geriatr, Honolulu, HI USA

[3] Dartmouth Hitchcock Med Ctr, Dept Med, Lebanon, NH 03766 USA

[4] Chubu Hosp, Dept Internal Med, Okinawa, Japan

[5] Chubu Hosp, Dept Pathol, Okinawa, Japan

[6] Okinawa Int Univ, Okinawa Res Ctr Longev Sci, Okinawa, Japan

[7] Okinawa Prefectural Univ, Coll Nursing, Okinawa, Japan

[8] Wellesley Coll, Wellesley, MA 02181 USA

[9] Boston Univ, Sch Med, Boston, MA 02215 USA

[10] Boston Med Ctr, Boston, MA 02215 USA

来源：

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2004年 / 59卷 / 11期

关键词：

D O I：

10.1093/gerona/59.11.1195

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Consistent with the compression-of-morbidity hypothesis, several studies have reported that a significant proportion of centenarians delay or escape age-related diseases. Of those who live with such diseases for a long time, many appear to do so with better functional status than do younger persons who do not achieve extreme old age. The authors describe the first autopsy in an Okinawan-Japanese centenarian who escaped many age-related illnesses and delayed frailty toward the end of her very long life. Her late-life morbidity pattern is contrasted with that of white centenarians.

引用

页码：1195 / 1199

页数：5

共 26 条

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