The Middle East Respiratory Syndrome (MERS)

被引：168

作者：

Azhar, Esam I. ^{[1
]}

Hui, David S. C. ^{[2
]}

Memish, Ziad A. ^{[3
,4
]}

Drosten, Christian ^{[5
]}

Zumla, Alimuddin ^{[6
]}

机构：

[1] King Abdulaziz Univ, Fac Appl Med Sci, Special Infect Agents Unit, King Fand Med Res Ctr, Jeddah, Saudi Arabia

[2] Chinese Univ Hong Kong, Dept Med & Therapeut, Stanley Ho Ctr Emerging Infect Dis, Shatin, Hong Kong, Peoples R China

[3] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia

[4] Prince Mohamed Bin Abdulaziz Hosp, Infect Dis Div, Dept Med & Res, Minist Hlth, Riyadh, Saudi Arabia

[5] Charite Univ Med Berlin, Inst Virol, Berlin Inst Hlth, Campus Charite Mitte, Berlin, Germany

[6] UCL, Ctr Clin Microbiol, Royal Free Campus,2nd Floor,Rowland Hill St, London NW3 2PF, England

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2019年 / 33卷 / 04期

基金：

欧盟地平线“2020”;

关键词：

Middle East respiratory syndrome coronavirus; MERS-CoV; Epidemiology diagnosis; Treatment; SYNDROME CORONAVIRUS TRANSMISSION; CRITICALLY-ILL PATIENTS; SAUDI-ARABIA; FAMILY CLUSTER; COV INFECTION; SURVEILLANCE; ANTIBODIES; OUTBREAK; HUMANS; CAMELS;

D O I：

10.1016/j.idc.2019.08.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The Middle East respiratory syndrome (MERS) is a novel lethal zoonotic disease of humans caused by the MERS coronavirus (MERS-CoV). Although MERS is endemic to the Middle East, travelers have exported MERS-CoV on return to their home countries. Clinical manifestations range from mild to severe acute respiratory disease and death. The elderly, immunocompromised, and those with chronic comorbid liver, lung, and hepatic conditions have a high mortality rate. There is no specific treatment. Person-to-person spread causes hospital and household outbreaks, and thus improved compliance with internationally recommended infection control protocols and rapid implementation of infection control measures are required.

引用

页码：891 / +

页数：16

共 59 条

[1] MERS: Progress on the global response, remaining challenges and the way forward
Aguanno, Ryan
Elldrissi, Ahmed
Elkholy, Amgad A.
Ben Embarek, Peter
Gardner, Emma
Grant, Rebecca
Mahrous, Heba
Malik, Mamunur Rahman
Pavade, Gounalan
VonDobschuetz, Sophie
Wiersma, Lidewij
Van Kerkhove, Maria D.
[J]. ANTIVIRAL RESEARCH, 2018, 159 : 35 - 44
[2] The predictors of 3-and 30-day mortality in 660 MERS-CoV patients
Ahmed, Anwar E.
[J]. BMC INFECTIOUS DISEASES, 2017, 17
[3] Asymptomatic MERS-CoV Infection in Humans Possibly Linked to Infected Dromedaries Imported from Oman to United Arab Emirates, May 2015
Al Hammadi, Zulaikha M.
Chu, Daniel K. W.
Eltahir, Yassir M.
Al Hosani, Farida
Al Mulla, Mariam
Tarnini, Wasim
Hall, Aron J.
Perera, Ranawaka A. P. M.
Abdelkhalek, Mohamed M.
Peiris, J. S. M.
Al Muhairi, Salama S.
Poon, Leo L. M.
[J]. EMERGING INFECTIOUS DISEASES, 2015, 21 (12) : 2197 - 2200
[4] Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description
Al-Abdallat, Mohammad Mousa
Payne, Daniel C.
Alqasrawi, Sultan
Rha, Brian
Tohme, Rania A.
Abedi, Glen R.
Al Nsour, Mohannad
Iblan, Ibrahim
Jarour, Najwa
Farag, Noha H.
Haddadin, Aktham
Al-Sanouri, Tarek
Tamin, Azaibi
Harcourt, Jennifer L.
Kuhar, David T.
Swerdlow, David L.
Erdman, Dean D.
Pallansch, Mark A.
Haynes, Lia M.
Gerber, Susan I.
[J]. CLINICAL INFECTIOUS DISEASES, 2014, 59 (09) : 1225 - 1233
[5] Scope and extent of healthcare-associated Middle East respiratory syndrome coronavirus transmission during two contemporaneous outbreaks in Riyadh, Saudi Arabia, 2017
Alanazi, Khalid H.
Killerby, Marie E.
Biggs, Holly M.
Abedi, Glen R.
Jokhdar, Hani
Alsharef, Ali A.
Mohammed, Mutaz
Abdalla, Osman
Almari, Aref
Bereagesh, Samar
Tawfik, Sameh
Alresheedi, Husain
Alhakeem, Raafat F.
Hakawi, Ahmed
Alfalah, Haitham
Amer, Hala
Thornburg, Natalie J.
Tamin, Azaibi
Trivedi, Suvang
Tong, Suxiang
Lu, Xiaoyan
Queen, Krista
Li, Yan
Sakthivel, Senthilkumar K.
Tao, Ying
Zhang, Jing
Paden, Clinton R.
Al-Abdely, Hail M.
Assiri, Abdullah M.
Gerber, Susan I.
Watson, John T.
[J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2019, 40 (01) : 79 - 88
[6] Macrolides in critically ill patients with Middle East Respiratory Syndrome
Arabi, Yaseen M.
Deeb, Ahmad M.
Al-Hameed, Fahad
Mandourah, Yasser
Almekhlafi, Ghaleb A.
Sindi, Anees A.
Al-Omari, Awad
Shalhoub, Sarah
Mady, Ahmed
Alraddadi, Basem
Almotairi, Abdullah
Al Khatib, Kasim
Abdulmomen, Ahmed
Qushmaq, Ismael
Solaiman, Othman
Al-Aithan, Abdulsalam M.
Al-Raddadi, Rajaa
Ragab, Ahmad
Al Harthy, Abdulrahman
Kharaba, Ayman
Jose, Jesna
Dabbagh, Tarek
Fowler, Robert A.
Balkhy, Hanan H.
Merson, Laura
Hayden, Frederick G.
[J]. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2019, 81 : 184 - 190
[7] Corticosteroid Therapy for Critically Ill Patients with Middle East Respiratory Syndrome
Arabi, Yaseen M.
Mandourah, Yasser
Al-Hameed, Fahad
Sindi, Anees A.
Almekhlafi, Ghaleb A.
Hussein, Mohamed A.
Jose, Jesna
Pinto, Ruxandra
Al-Omari, Awad
Kharaba, Ayman
Almotairi, Abdullah
Al Khatib, Kasim
Alraddadi, Basem
Shalhoub, Sarah
Abdulmomen, Ahmed
Qushmaq, Ismael
Mady, Ahmed
Solaiman, Othman
Al-Aithan, Abdulsalam M.
Al-Raddadi, Rajaa
Ragab, Ahmed
Balkhy, Hanan H.
Al Harthy, Abdulrahman
Deeb, Ahmad M.
Al Mutairi, Hanan
Al-Dawood, Abdulaziz
Merson, Laura
Hayden, Frederick G.
Fowler, Robert A.
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197 (06) : 757 - 767
[8] Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial
Arabi, Yaseen M.
Alothman, Adel
Balkhy, Hanan H.
Al-Dawood, Abdulaziz
AlJohani, Sameera
Al Harbi, Shmeylan
Kojan, Suleiman
Al Jeraisy, Majed
Deeb, Ahmad M.
Assiri, Abdullah M.
Al-Hameed, Fahad
AlSaedi, Asim
Mandourah, Yasser
Almekhlafi, Ghaleb A.
Sherbeeni, Nisreen Murad
Elzein, Fatehi Elnour
Memon, Javed
Taha, Yusri
Almotairi, Abdullah
Maghrabi, Khalid A.
Qushmaq, Ismael
Al Bshabshe, Ali
Kharaba, Ayman
Shalhoub, Sarah
Jose, Jesna
Fowler, Robert A.
Hayden, Frederick G.
Hussein, Mohamed A.
[J]. TRIALS, 2018, 19
[9] Critically Ill Patients With the Middle East Respiratory Syndrome: A Multicenter Retrospective Cohort Study
Arabi, Yaseen M.
Al-Omari, Awad
Mandourah, Yasser
Al-Hameed, Fahad
Sindi, Anees A.
Alraddadi, Basem
Shalhoub, Sarah
Almotairi, Abdullah
Al Khatib, Kasim
Abdulmomen, Ahmed
Qushmaq, Ismael
Mady, Ahmed
Solaiman, Othman
Al-Aithan, Abdulsalam M.
Al-Raddadi, Rajaa
Ragab, Ahmed
Al Mekhlafi, Ghaleb. A.
Al Harthy, Abdulrahman
Kharaba, Ayman
Al Ahmadi, Mashael
Sadat, Musharaf
Al Mutairi, Hanan
Al Qasim, Eman
Jose, Jesna
Nasim, Maliha
Al-Dawood, Abdulaziz
Merson, Laura
Fowler, Robert
Hayden, Frederick G.
Balkhy, Hanan H.
[J]. CRITICAL CARE MEDICINE, 2017, 45 (10) : 1683 - 1695
[10] Middle East Respiratory Syndrome
Arabi, Yaseen M.
Balkhy, Hanan H.
Hayden, Frederick G.
Bouchama, Abderrezak
Luke, Thomas
Baillie, J. Kenneth
Al-Omari, Awad
Hajeer, Ali H.
Senga, Mikiko
Denison, Mark R.
Nguyen-Van-Tam, Jonathan S.
Shindo, Nahoko
Bermingham, Alison
Chappell, James D.
Van Kerkhove, Maria D.
Fowler, Robert A.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (06) : 584 - 594

← 1 2 3 4 5 6 →