HemI: A Toolkit for Illustrating Heatmaps

被引:865
作者
Deng, Wankun [1 ]
Wang, Yongbo [1 ]
Liu, Zexian [1 ]
Cheng, Han [1 ]
Xue, Yu [1 ]
机构
[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Dept Biomed Engn, Wuhan 430074, Hubei, Peoples R China
来源
PLOS ONE | 2014年 / 9卷 / 11期
基金
对外科技合作项目(国际科技项目); 中国博士后科学基金;
关键词
MICROARRAY DATA; GENERATION;
D O I
10.1371/journal.pone.0111988
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under different conditions. In this work, we developed an easy-touse tool named Hemi (Heat map Illustrator), which can visualize either gene or protein expression data in heatmaps. Additionally, the heatmaps can be recolored, rescaled or rotated in a customized manner. In addition, Hemi provides multiple clustering strategies for analyzing the data. Publication-quality figures can be exported directly. We propose that Hemi can be a useful toolkit for conveniently visualizing and manipulating heatmaps. The stand-alone packages of Hemi were implemented in Java and can be accessed at http://hemi.biocuckoo.org/down.php.
引用
收藏
页数:5
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