The influence of neuropeptides on Malpighian tubule writhing and its significance for excretion

被引:33
作者
Coast, GM [1 ]
机构
[1] Univ London Birkbeck Coll, Dept Biol, London WC1E 7HZ, England
基金
英国生物技术与生命科学研究理事会;
关键词
Locusta migratoria; Malpighian tubules; visceral muscle; fluid secretion; Locusta diuretic hormone; locustakinin; diuretic hormone; myotropic peptides; excretion;
D O I
10.1016/S0196-9781(97)00461-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Diuretic peptides (locustakinin and Locusta-DH) increase the spontaneous contractile activity of visceral muscle fibers associated with Malpighian tubules from the migratory locust (Locusta migrator ia) at concentrations that increase urine production. Muscle activity is shown to assist the flow of material in the tubule lumen, but is not essential for diuresis. Tubule writhing also serves to reduce unstirred layers (USLs) at the basolateral surface of the epithelium and thereby facilitates the excretion of solutes entering the lumen by passive diffusion. (C) 1998 Elsevier Science Inc.
引用
收藏
页码:469 / 480
页数:12
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