DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates

被引：69

作者：

Patel, R

Uhl, JR

Kohner, P

Hopkins, MK

Steckelberg, JM

Kline, B

Cockerill, FR

机构：

[1] Mayo Clin & Mayo Fdn, Div Clin Microbiol, Rochester, MN 55902 USA

[2] Mayo Clin & Mayo Fdn, Div Mol Biol, Rochester, MN 55902 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 01期

关键词：

D O I：

10.1128/AAC.42.1.202

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.

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页码：202 / 205

页数：4

相关论文

共 7 条

[1] THE VANB GENE OF VANCOMYCIN-RESISTANT ENTEROCOCCUS-FAECALIS V583 IS STRUCTURALLY RELATED TO GENES ENCODING D-ALA D-ALA LIGASES AND GLYCOPEPTIDE-RESISTANCE PROTEINS VANA AND VANC [J].

EVERS, S ;

SAHM, DF ;

COURVALIN, P .

GENE, 1993, 124 (01) :143-144

[2] SEQUENCE OF THE VANB AND DDL GENES ENCODING D-ALANINE-D-LACTATE AND D-ALANINE-D-ALANINE LIGASES IN VANCOMYCIN-RESISTANT ENTEROCOCCUS-FAECALIS V583 [J].

EVERS, S ;

REYNOLDS, PE ;

COURVALIN, P .

GENE, 1994, 140 (01) :97-102

[3] A GENE CONFERRING RESISTANCE TO VANCOMYCIN BUT NOT TEICOPLANIN IN ISOLATES OF ENTEROCOCCUS-FAECALIS AND ENTEROCOCCUS-FAECIUM DEMONSTRATES HOMOLOGY WITH VANB, VANA, AND VANC GENES OF ENTEROCOCCI [J].

GOLD, HS ;

UNAL, S ;

CERCENADO, E ;

THAUVINELIOPOULOS, C ;

ELIOPOULOS, GM ;

WENNERSTEN, CB ;

MOELLERING, RC .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (08) :1604-1609

[4] INVIVO DEVELOPMENT OF TEICOPLANIN RESISTANCE IN A VANB ENTEROCOCCUS-FAECIUM ISOLATE [J].

HAYDEN, MK ;

TRENHOLME, GM ;

SCHULTZ, JE ;

SAHM, DF .

JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (05) :1224-1227

[5] Multiplex PCR detection of vanA, vanB, vanC-1, and vanC-2/3 genes in enterococci [J].

Patel, R ;

Uhl, JR ;

Kohner, P ;

Hopkins, MK ;

Cockerill, FR .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (03) :703-707

[6] INDUCIBLE AND CONSTITUTIVE EXPRESSION OF VANC-1-ENCODED RESISTANCE TO VANCOMYCIN IN ENTEROCOCCUS-GALLINARUM [J].

SAHM, DF ;

FREE, L ;

HANDWERGER, S .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (07) :1480-1484

[7] INTERPRETING CHROMOSOMAL DNA RESTRICTION PATTERNS PRODUCED BY PULSED-FIELD GEL-ELECTROPHORESIS - CRITERIA FOR BACTERIAL STRAIN TYPING [J].

TENOVER, FC ;

ARBEIT, RD ;

GOERING, RV ;

MICKELSEN, PA ;

MURRAY, BE ;

PERSING, DH ;

SWAMINATHAN, B .

JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (09) :2233-2239