Antioxidant activity of Baccharis articulata extracts:: Isolation of a new compound with antioxidant activity

被引：29

作者：

De Oliveira, SQ

Dal-Pizzol, F

Gosmann, G

Guillaume, D

Moreira, JCF

Schenkel, EP

机构：

[1] Univ Fed Rio Grande Sul, Fac Farm, BR-90610000 Porto Alegre, RS, Brazil

[2] Univ Fed Rio Grande Sul, Dept Bioquim, Lab Estresse Oxidativo, BR-90610000 Porto Alegre, RS, Brazil

[3] Univ Extremo Sul Catarinense, Dept Med, Criciuma, Brazil

[4] UPJV, Fac Pharm, Lab Chim Therapeut, Amiens, France

[5] Univ Fed Santa Catarina, Ctr Ciencias Saude, Florianopolis, SC, Brazil

来源：

FREE RADICAL RESEARCH | 2003年 / 37卷 / 05期

关键词：

Baccharis; Baccharis articulata; antioxidant; free radicals; plant phenols; n-butanol fraction;

D O I：

10.1080/1071576031000076259

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Baccharis articulata is traditionally used as diuretic and digestive in local folk medicine of south of Brazil, Uruguay and Argentina. The antioxidant activity of crude ethanol and aqueous extracts, together with dichloromethane, ethyl acetate and n-butanol fractions obtained from aqueous extract of B. articulata was determined using TRAP and TBARS assays. The n-butanol fraction was found to be the most active and its major compound (Ball) was isolated, identified and assayed. The structure of the phenolic compound Ball was established by means of spectroscopic and chemical methods as 4'-O-beta-D-glucopyranosyl-3',5'-dimethoxybenzyl-caffeate. This previously unreported metabolite presented similar antioxidant capacity when compared to Trolox.

引用

页码：555 / 559

页数：5

共 17 条

[1] CLERODANE DITERPENOIDS FROM BACCHARIS-ARTICULATA [J].