Fluorescence correlation spectroscopy using quantum dots: advances, challenges and opportunities

被引：77

作者：

Heuff, Romey F. ^{[1
]}

Swift, Jody L. ^{[1
]}

Cramb, David T. ^{[1
]}

机构：

[1] Univ Calgary, Dept Chem, Calgary, AB T2N 1N4, Canada

来源：

PHYSICAL CHEMISTRY CHEMICAL PHYSICS | 2007年 / 9卷 / 16期

关键词：

D O I：

10.1039/b617115j

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Semiconductor nanocrystals ( quantum dots) have been increasingly employed in measuring the dynamic behavior of biomacromolecules using. uorescence correlation spectroscopy. This poses a challenge, because quantum dots display their own dynamic behavior in the form of intermittent photoluminescence, also known as blinking. In this review, the manifestation of blinking in correlation spectroscopy will be explored, preceded by an examination of quantum dot blinking in general.

引用

页码：1870 / 1880

页数：11

共 70 条

[1] The use of nanocrystals in biological detection [J].

Alivisatos, P .

NATURE BIOTECHNOLOGY, 2004, 22 (01) :47-52

[2] Characterization of blinking dynamics in quantum dot ensembles using image correlation spectroscopy [J].

Bachir, AI ;

Durisic, N ;

Hebert, B ;

Grütter, P ;

Wiseman, PW .

JOURNAL OF APPLIED PHYSICS, 2006, 99 (06)

[3] Quantum dot anti-CD conjugates: Are they potential photosensitizers or potentiators of classical photosensitizing agents in photodynamic therapy of cancer? [J].

Bakalova, R ;

Ohba, H ;

Zhelev, Z ;

Nagase, T ;

Jose, R ;

Ishikawa, M ;

Baba, Y .

NANO LETTERS, 2004, 4 (09) :1567-1573

[4] Evidence for a thermal contribution to emission intermittency in single CdSe/CdS core/shell nanocrystals [J].

Banin, U ;

Bruchez, M ;

Alivisatos, AP ;

Ha, T ;

Weiss, S ;

Chemla, DS .

JOURNAL OF CHEMICAL PHYSICS, 1999, 110 (02) :1195-1201

[5] Excitation saturation in two-photon fluorescence correlation spectroscopy [J].

Berland, K ;

Shen, GQ .

APPLIED OPTICS, 2003, 42 (27) :5566-5576

[6] Measurement of the radiative and nonradiative decay rates of single CdSe nanocrystals through a controlled modification of their spontaneous emission [J].

Brokmann, X ;

Coolen, L ;

Dahan, M ;

Hermier, JP .

PHYSICAL REVIEW LETTERS, 2004, 93 (10) :107403-1

[7] The effects of chemisorption on the luminescence of CdSe quantum dots [J].

Bullen, C ;

Mulvaney, P .

LANGMUIR, 2006, 22 (07) :3007-3013

[8] Luminescent quantum dots for multiplexed biological detection and imaging [J].

Chan, WCW ;

Maxwell, DJ ;

Gao, XH ;

Bailey, RE ;

Han, MY ;

Nie, SM .

CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (01) :40-46

[9] Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].

Chan, WCW ;

Nie, SM .

SCIENCE, 1998, 281 (5385) :2016-2018

[10] Fluorescent CdSe/ZnS nanocrystal-peptide conjugates for long-term, nontoxic imaging and nuclear targeting in living cells [J].

Chen, FQ ;

Gerion, D .

NANO LETTERS, 2004, 4 (10) :1827-1832

← 1 2 3 4 5 6 7 →