Recent developments in detection for microfluidic systems

被引:190
作者
Mogensen, KB [1 ]
Klank, H [1 ]
Kutter, JP [1 ]
机构
[1] Tech Univ Denmark, Dept Micro & Nanotechnol, MIC, DK-2800 Lyngby, Denmark
关键词
mass spectrometry; microfluidics; miniaturization; review; waveguides;
D O I
10.1002/elps.200406108
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Microfluidic systems have become more and more important in the field of analytical chemistry. Detection methods on these microsystems are essential for the identification and quantification of chemical species that are being analyzed. This review concentrates on the latest developments of optical detection methods and mass spectrometry in conjunction with microfluidic systems. Electrochemical methods are discussed in another review in the same issue of this journal. Within the optical detection section, topics such as multiplexed detection and the use of waveguides are discussed. Within the discussion of mass spectrometry, the main focus is on electrospray emitters as interfaces between microsystern and spectrometer. Apart from optical detection and mass spectrometry, other techniques such as flame ionization and nuclear magnetic resonance are also mentioned.
引用
收藏
页码:3498 / 3512
页数:15
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