Silica-promoted facile synthesis of thioesters and thioethers: a highly efficient, reusable and environmentally safe solid support

被引：68

作者：

Basu, Basudeb ^{[1
]}

Paul, Susmita ^{[1
]}

Nanda, Ashis K. ^{[1
]}

机构：

[1] N Bengal Univ, Dept Chem, Darjeeling 734013, India

来源：

GREEN CHEMISTRY | 2010年 / 12卷 / 05期

关键词：

CHLORIDE CATALYZED ACYLATION; SOLVENT-FREE; S-ALKYLATION; MICHAEL ADDITION; ACID ANHYDRIDES; ALCOHOLS; THIOLS; AMINES; PHENOLS; ACETYLATION;

D O I：

10.1039/b925620b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient, mild and rapid procedure for the acylation and alkylation of aromatic and aliphatic thiols mediated on a silica gel surface at room temperature is described. The protocol allows the protection of thiols under neutral heterogeneous conditions without requiring any bases or Lewis acids, and the silica gel used as the promoter can be recycled for several runs without any loss of activity.

引用

页码：767 / 771

页数：5