Molecular recognition in fungal mating

Fungal cells need to recognize that they are genetically different in order to mate. Cells signal to each other by secreting small peptide pheromones which are detected by cell surface receptors. New transcriptional regulators are formed that alter the pattern of gene transcription. Basidiomycete fungi are unusual in having several thousands of different mating types. In these fungi, mating partner recognition demands a remarkable degree of specificity on the part of the proteins and peptides involved.