Cross-species comparisons of cancer signaling

被引：18

作者：

Graeber, TG ^{[1
]}

Sawyers, CL

机构：

[1] Univ Calif Los Angeles, Crump Inst Mol & Med Pharmacol, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Mol & Med Pharmacol, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90095 USA

[4] Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA

来源：

NATURE GENETICS | 2005年 / 37卷 / 01期

关键词：

D O I：

10.1038/ng0105-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Modeling of human cancer in genetically engineered mice and genome-wide measurements of mRNA expression have now been combined to accelerate the search for new molecularly targeted therapies against cancer. Looking forward, we propose a community-wide systematic effort to model and characterize an array of different cancer-related aberrant signaling pathways in several mouse models of cancer.

引用

页码：7 / 8

页数：2

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