Chemokines and their receptors in allograft rejection

被引:150
作者
Hancock, WW [1 ]
Gao, W [1 ]
Faia, KL [1 ]
Csizmadia, V [1 ]
机构
[1] Millennium Pharmaceut Inc, Cambridge, MA 02139 USA
关键词
D O I
10.1016/S0952-7915(00)00130-8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Despite current recognition of over 40 chemokines and more than 18 chemokine receptors, understanding of their role in transplant immunobiology and transplant rejection is extremely limited and fragmentary. Recent literature has demonstrated the presence of chemokines and their receptors in transplants and some studies demonstrate important functional roles.
引用
收藏
页码:511 / 516
页数:6
相关论文
共 38 条
[1]  
Azzawi M, 1998, J HEART LUNG TRANSPL, V17, P881
[2]   Nature and mediators of renal lesions in kidney transplant patients given cyclosporine for more than one year [J].
Benigni, A ;
Bruzzi, I ;
Mister, M ;
Azzollini, N ;
Gaspari, F ;
Perico, N ;
Gotti, E ;
Bertani, T ;
Remuzzi, G .
KIDNEY INTERNATIONAL, 1999, 55 (02) :674-685
[3]   Upregulation of T-helper 1 cytokines and chemokine expression in post-transplant airway obliteration [J].
Boehler, A ;
Bai, XH ;
Liu, MY ;
Cassivi, S ;
Chamberlain, D ;
Slutsky, AS ;
Keshavjee, S .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (06) :1910-1917
[4]   Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s [J].
Bonecchi, R ;
Bianchi, G ;
Bordignon, PP ;
D'Ambrosio, D ;
Lang, R ;
Borsatti, A ;
Sozzani, S ;
Allavena, P ;
Gray, PA ;
Mantovani, A ;
Sinigaglia, F .
JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 187 (01) :129-134
[5]   Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis [J].
Boring, L ;
Gosling, J ;
Cleary, M ;
Charo, IF .
NATURE, 1998, 394 (6696) :894-897
[6]   RANTES and MCP-1 chemokine plasma levels in chronic renal transplant dysfunction and chronic renal failure [J].
Corsi, MM ;
Leone, G ;
Fulgenzi, A ;
Wasserman, K ;
Leone, F ;
Ferrero, ME .
CLINICAL BIOCHEMISTRY, 1999, 32 (06) :455-460
[7]   Chemokine receptor (CXCR4) mRNA-expressing leukocytes are increased in human renal allograft rejection [J].
Eitner, F ;
Cui, Y ;
Hudkins, KL ;
Alpers, CE .
TRANSPLANTATION, 1998, 66 (11) :1551-1557
[8]   Chemokine receptor (CCR5) expression in human kidneys and in the HIV infected macaque [J].
Eitner, F ;
Cui, Y ;
Hudkins, KL ;
Anderson, DM ;
Schmidt, A ;
Morton, WR ;
Alpers, CE .
KIDNEY INTERNATIONAL, 1998, 54 (06) :1945-1954
[9]   Expression and modulation of ICAM-1, TNF-α and RANTES in human alveolar macrophages from lung-transplant recipients in vitro [J].
Fattal-German, M ;
Ladurie, FL ;
Cerrina, J ;
Lecerf, F ;
Berrih-Aknin, S .
TRANSPLANT IMMUNOLOGY, 1998, 6 (03) :183-192
[10]   Analysis of intragraft cytokine expression during early reperfusion after liver transplantation using semi-quantitative RT-PCR [J].
Flach, R ;
Speidel, N ;
Flohe, S ;
Borgermann, J ;
Dresen, IG ;
Erhard, J ;
Schade, FU .
CYTOKINE, 1998, 10 (06) :445-451