Manipulation of innate immunity by bacterial pathogens

被引：36

作者：

Portnoy, DA ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94703 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2005年 / 17卷 / 01期

关键词：

D O I：

10.1016/j.coi.2004.11.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The past decade has witnessed tremendous growth in two related fields: innate immunity and microbial pathogenesis. Many pathogens have evolved mechanisms to infect their hosts in the face of a fully functional innate immune system, and there are numerous examples by which pathogens avoid recognition and/or suppress inflammation. In this review, I suggest that pathogens not only survive the innate immune response, but use it to promote their pathogenesis.

引用

页码：25 / 28

页数：4

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