Ribosomal RNA processing and ribosome biogenesis in eukaryotes

被引:87
作者
Nazar, RN [1 ]
机构
[1] Univ Guelph, Dept Mol Biol & Genet, Guelph, ON N1G 2W1, Canada
关键词
ribosomes; eukaryotes; nucleolus; rRNA; RNA processing; snoRNA; nucleolar proteins;
D O I
10.1080/15216540400010867
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In eukaryotes nearly 500 rRNAs, ribosomal proteins, snoRNAs and trans-acting factors contribute to ribosome biogenesis. After more than 30 years of intense research, the incredible complexities of nucleolar function are revealed but details often remain unclear. Here we review this progress and the many intriguing questions which remain.
引用
收藏
页码:457 / 465
页数:9
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