Platination of nucleobases to enhance noncovalent recognition in protein-DNA/RNA complexes

被引：17

作者：

Anzellotti, AI ^{[1
]}

Ma, ES ^{[1
]}

Farrell, N ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Dept Chem, Richmond, VA 23284 USA

来源：

INORGANIC CHEMISTRY | 2005年 / 44卷 / 03期

关键词：

D O I：

10.1021/ic049086d

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Fluorescence quenching experiments show that the stacking interaction between nucleic acid bases and I-tryptophan is enhanced significantly upon base coordination to a metal center such as Pt(II), and the biological implications of such enhancement are discussed.

引用

页码：483 / 485

页数：3

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