An LEA group 3 family member is involved in survival of C-elegans during exposure to stress

被引：118

作者：

Gal, TZ

Glazer, I

Koltai, H ^{[1
]}

机构：

[1] Agr Res Org, Volcani Ctr, Dept Genom, IL-50250 Bet Dagan, Israel

[2] Agr Res Org, Volcani Ctr, Dept Nematol, IL-50250 Bet Dagan, Israel

来源：

FEBS LETTERS | 2004年 / 577卷 / 1-2期

关键词：

Ce-lea-1; Ce-lin-53; Ce-unc-120; desiccation stress; heat stress; osmotic stress;

D O I：

10.1016/j.febslet.2004.09.049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In order to establish a functional role for late embryogenesis abundant (LEA) proteins in response to stress conditions in Caenorhabditis elegans, we silenced the expression of an LEA (Ce-lea-1) gene and determined the survival of worms under stress conditions. Ce-lea-1 transcription was induced during dehydration of C. elegans dauer juveniles. Following partial silencing of Ce-lea-1 transcription, we demonstrated a specific and significant reduction in worm survival during induction of desiccation, osmotic and heat stress. Together, these results establish a functional role for Ce-lea-1 in stress survival of C elegans and suggest that Ce-lea-1 may function as a component that is common to the responses to the examined stress conditions. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：21 / 26

页数：6

共 48 条

[1] Osmotic regulation in adult Drosophila melanogaster during dehydration and rehydration [J].