Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis

被引：20

作者：

Booth, David R. ^{[2
]}

Heard, Robert N. ^{[2
]}

Stewart, Graeme J. ^{[2
]}

Cox, Mathew ^{[3
]}

Scott, Rodney J. ^{[3
]}

Lechner-Scott, Jeannette ^{[3
]}

Goris, An ^{[4
]}

Dobosi, Rita ^{[4
]}

Dubois, Benedicte ^{[4
]}

Saarela, Janna ^{[5
,6
]}

Leppa, Virpi ^{[5
,6
]}

Peltonen, Leena ^{[6
,7
]}

Pirttila, Tuula ^{[8
]}

Cournu-Rebeix, Isabelle ^{[9
,10
]}

Fontaine, Bertrand ^{[9
,10
]}

Bergamaschi, Laura ^{[11
,12
]}

D'Alfonso, Sandra ^{[11
,12
]}

Leone, Maurizio ^{[13
]}

Lorentzen, Aslaug R. ^{[14
,15
]}

Harbo, Hanne F. ^{[14
]}

Celius, Elisabeth G. ^{[14
]}

Spurkland, Anne ^{[16
]}

Link, Jenny ^{[17
]}

Kockum, Ingrid ^{[17
]}

Olsson, Tomas ^{[17
]}

Hillert, Jan ^{[17
]}

Ban, Maria ^{[1
]}

Baker, Amie ^{[1
]}

Kemppinen, Anu ^{[1
]}

Sawcer, Stephen ^{[1
]}

Compston, Alastair ^{[1
]}

Robertson, Neil P. ^{[18
]}

De Jager, Philip L. ^{[19
,20
,21
]}

Hafler, David A. ^{[20
,21
,22
]}

Barcellos, Lisa F. ^{[23
]}

Ivinson, Adrian J. ^{[24
]}

McCauley, Jacob L. ^{[25
]}

Pericak-Vance, Margaret A. ^{[25
]}

Oksenberg, Jorge R. ^{[26
]}

Hauser, Stephen L. ^{[26
]}

Sexton, David ^{[27
]}

Haines, Jonathan ^{[27
]}

机构：

[1] Univ Cambridge, Addenbrookes Hosp, Dept Clin Neurosci, Cambridge CB2 2QQ, England

[2] Univ Sydney, Westmead Hosp, Westmead Millennium Inst, Inst Immunol & Allergy Res, Sydney, NSW 2006, Australia

[3] Univ Newcastle, Hunter Med Res Inst, Callaghan, NSW 2308, Australia

[4] Katholieke Univ Leuven, Sect Expt Neurol, Louvain, Belgium

[5] Natl Inst Hlth & Welf, Publ Hlth Genom Unit, Helsinki, Finland

[6] Univ Helsinki, FIMM, Helsinki, Finland

[7] Wellcome Trust Sanger Inst, Cambridge, England

[8] Univ Kuopio, Cent Hosp, Dept Neurol, Kuopio, Finland

[9] Univ Paris 06, Ctr Rech, INSERM, Inst Cerveau & Moelle,UMR S975, Paris, France

[10] Hop La Pitie Salpetriere, AP HP, Paris, France

[11] Univ Piemonte Orientale, Dept Med Sci, Novara, Italy

[12] Univ Piemonte Orientale, Interdisciplinary Res Ctr Autoimmune Dis, Novara, Italy

[13] Osped Maggiore La Carita, Neurol Clin, Novara, Italy

[14] Univ Oslo, Dept Neurol, Oslo, Norway

[15] Oslo Univ Hosp, Inst Immunol, Oslo, Norway

[16] Univ Oslo, Inst Basic Med Sci, Oslo, Norway

[17] Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden

[18] Univ Wales Hosp, Dept Neurol, Cardiff CF4 4XW, S Glam, Wales

[19] Brigham & Womens Hosp, Dept Neurol, Program Translat NeuroPsychiat Genom, Boston, MA 02115 USA

[20] Harvard Univ, Broad Inst, Cambridge, MA 02138 USA

[21] MIT, Cambridge, MA 02139 USA

[22] Yale Univ, Sch Med, Dept Neurol, New Haven, CT 06510 USA

[23] Univ Calif Berkeley, Sch Publ Hlth, Div Epidemiol, Berkeley, CA 94720 USA

[24] Harvard Univ, Sch Med, Harvard NeuroDiscovery Ctr, Boston, MA USA

[25] Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA

[26] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA

[27] Vanderbilt Univ, Med Ctr, Ctr Human Genet Res, Nashville, TN USA

来源：

NATURE GENETICS | 2010年 / 42卷 / 06期

基金：

英国惠康基金;

关键词：

SUSCEPTIBILITY;

D O I：

10.1038/ng0610-469

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：469 / 470

页数：2

共 5 条

[1] Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis [J].

Aulchenko, Yurii S. ;

Hoppenbrouwers, Ilse A. ;

Ramagopalan, Sreeram V. ;

Broer, Linda ;

Jafari, Naghmeh ;

Hillert, Jan ;

Link, Jenny ;

Lundstrom, Wangko ;

Greiner, Eva ;

Sadovnick, A. Dessa ;

Goossens, Dirk ;

Van Broeckhoven, Christine ;

Del-Favero, Jurgen ;

Ebers, George C. ;

Oostra, Ben A. ;

van Duijn, Cornelia M. ;

Hintzen, Rogier Q. .

NATURE GENETICS, 2008, 40 (12) :1402-1403

[2] Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20 [J].

Bahlo, Melanie ;

Booth, David R. ;

Broadley, Simon A. ;

Brown, Matthew A. ;

Foote, Simon J. ;

Griffiths, Lyn R. ;

Kilpatrick, Trevor J. ;

Lechner-Scott, Jeanette ;

Moscato, Pablo ;

Perreau, Victoria M. ;

Rubio, Justin P. ;

Scott, Rodney J. ;

Stankovich, Jim ;

Stewart, Graeme J. ;

Taylor, Bruce V. ;

Wiley, James ;

Clarke, Glynnis ;

Cox, Mathew B. ;

Csurhes, Peter A. ;

Danoy, Patrick ;

Drysdale, Karen ;

Field, Judith ;

Foote, Simon J. ;

Greer, Judith M. ;

Guru, Preethi ;

Hadler, Johanna ;

McMorran, Brendan J. ;

Jensen, Cathy J. ;

Johnson, Laura J. ;

McCallum, Ruth ;

Merriman, Marilyn ;

Merriman, Tony ;

Pryce, Karen ;

Tajouri, Lotfi ;

Wilkins, Ella J. ;

Browning, Brian L. ;

Browning, Sharon R. ;

Perera, Devindri ;

Butzkueven, Helmut ;

Carroll, William M. ;

Chapman, Caron ;

Kermode, Allan G. ;

Marriott, Mark ;

Mason, Deborah ;

Heard, Robert N. ;

Pender, Michael P. ;

Slee, Mark ;

Tubridy, Niall ;

Willoughby, Ernest .

NATURE GENETICS, 2009, 41 (07) :824-U84

[3] Pedigree disequilibrium tests for multilocus haplotypes [J].

Dudbridge, F .

GENETIC EPIDEMIOLOGY, 2003, 25 (02) :115-121

[4] PLINK: A tool set for whole-genome association and population-based linkage analyses [J].

Purcell, Shaun ;

Neale, Benjamin ;

Todd-Brown, Kathe ;

Thomas, Lori ;

Ferreira, Manuel A. R. ;

Bender, David ;

Maller, Julian ;

Sklar, Pamela ;

de Bakker, Paul I. W. ;

Daly, Mark J. ;

Sham, Pak C. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2007, 81 (03) :559-575

[5] The complex genetics of multiple sclerosis: pitfalls and prospects [J].

Sawcer, Stephen .

BRAIN, 2008, 131 :3118-3131

← 1 →