The role of analytical sciences medical systems biology

被引:212
作者
van der Greef, J
Stroobant, P
van der Heijden, R
机构
[1] TNO, Syst Biol, NL-3700 AJ Zeist, Netherlands
[2] Beyond Genom Inc, Waltham, MA 02451 USA
[3] Gorlaeus Labs, LACDR, Ctr Med Syst Biol, NL-3700 RA Leiden, Netherlands
关键词
D O I
10.1016/j.cbpa.2004.08.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Medical systems biology has generated widespread interest because of its bold conception and exciting potential, but the field is still in its infancy. Although there has been tremendous progress achieved recently in generating, integrating and analysing data in the medical and pharmaceutical field, many challenges remain, especially with respect to the crucial core technologies required for analytical characterization. This review briefly summarizes these aspects for metabolomics, proteomics, data handling and multivariate biostatistics.
引用
收藏
页码:559 / 565
页数:7
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