Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage

被引:24
作者
Yan, Feng [1 ]
Yi, Zhang [2 ]
Hua, Yang [3 ]
Shen, Ying [4 ]
Li, Ming [5 ]
Ding, Yuchuan [5 ,6 ]
Chandra, Ankush [6 ,7 ]
Ji, Xunming [1 ]
Yue, Wei [8 ]
机构
[1] Capital Med Univ, Xuanwu Hosp, Dept Neurosurg, Beijing, Peoples R China
[2] Tianjin Huanhu Hosp, Drug Clin Trial Inst, Tianjin, Peoples R China
[3] Capital Med Univ, Xuanwu Hosp, Dept Ultrasound, Beijing, Peoples R China
[4] Capital Med Univ, Xuanwu Hosp, Dept Traditiona Chinese Med, Beijing, Peoples R China
[5] Capital Med Univ, Xuanwu Hosp, China Amer Inst Neurosci, Beijing, Peoples R China
[6] Wayne State Univ, Sch Med, Dept Neurosurg, Detroit, MI USA
[7] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA USA
[8] Tianjin Huanhu Hosp, Dept Neurol, Tianjin, Peoples R China
关键词
Intracerebral hemorrhage; mortality; hemorrhagic stroke; recurrent stroke; risk factors; prognosis; outcomes; LONG-TERM SURVIVAL; SEX-DIFFERENCES; MANAGEMENT; CHINA; SUBTYPES; TRENDS;
D O I
10.1080/01616412.2018.1451266
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Objective: There are limited studies exploring prognosis after intracerebral hemorrhage (ICH) in Chinese populations. Thus, we evaluated the risk factors and predictors of mortality and recurrent stroke in a large clinical cohort at a single institution. Methods: We analysed consecutive cases of spontaneous ICH at admission to our hospital from September 2010 to December 2016. Independent predictors of mortality at one month and five year follow-up, as well as stroke recurrence were analysed. Results: A total of 1187 cases were included (33.5% women). The one month case fatality rate was 12.5%, and the five year mortality rate was 22.2%. In the multivariate analysis, diabetes was an independent predictor of one month case fatality, and older age (z65 years) was an independent predictor of five year mortality. Brain stem hemorrhage and intraventricular hemorrhage were independent predictors of both short- and long-term mortality. The overall recurrence rate was 32.5% among one month survivors. Conclusion: Predictors of recurrent stroke were older females, hypertension, diabetes, and brain stem hemorrhage. These findings may help to determine specific treatment strategies and improve quality of health care for such patients.
引用
收藏
页码:466 / 472
页数:7
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