Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage

被引:24
作者
Yan, Feng [1 ]
Yi, Zhang [2 ]
Hua, Yang [3 ]
Shen, Ying [4 ]
Li, Ming [5 ]
Ding, Yuchuan [5 ,6 ]
Chandra, Ankush [6 ,7 ]
Ji, Xunming [1 ]
Yue, Wei [8 ]
机构
[1] Capital Med Univ, Xuanwu Hosp, Dept Neurosurg, Beijing, Peoples R China
[2] Tianjin Huanhu Hosp, Drug Clin Trial Inst, Tianjin, Peoples R China
[3] Capital Med Univ, Xuanwu Hosp, Dept Ultrasound, Beijing, Peoples R China
[4] Capital Med Univ, Xuanwu Hosp, Dept Traditiona Chinese Med, Beijing, Peoples R China
[5] Capital Med Univ, Xuanwu Hosp, China Amer Inst Neurosci, Beijing, Peoples R China
[6] Wayne State Univ, Sch Med, Dept Neurosurg, Detroit, MI USA
[7] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA USA
[8] Tianjin Huanhu Hosp, Dept Neurol, Tianjin, Peoples R China
关键词
Intracerebral hemorrhage; mortality; hemorrhagic stroke; recurrent stroke; risk factors; prognosis; outcomes; LONG-TERM SURVIVAL; SEX-DIFFERENCES; MANAGEMENT; CHINA; SUBTYPES; TRENDS;
D O I
10.1080/01616412.2018.1451266
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Objective: There are limited studies exploring prognosis after intracerebral hemorrhage (ICH) in Chinese populations. Thus, we evaluated the risk factors and predictors of mortality and recurrent stroke in a large clinical cohort at a single institution. Methods: We analysed consecutive cases of spontaneous ICH at admission to our hospital from September 2010 to December 2016. Independent predictors of mortality at one month and five year follow-up, as well as stroke recurrence were analysed. Results: A total of 1187 cases were included (33.5% women). The one month case fatality rate was 12.5%, and the five year mortality rate was 22.2%. In the multivariate analysis, diabetes was an independent predictor of one month case fatality, and older age (z65 years) was an independent predictor of five year mortality. Brain stem hemorrhage and intraventricular hemorrhage were independent predictors of both short- and long-term mortality. The overall recurrence rate was 32.5% among one month survivors. Conclusion: Predictors of recurrent stroke were older females, hypertension, diabetes, and brain stem hemorrhage. These findings may help to determine specific treatment strategies and improve quality of health care for such patients.
引用
收藏
页码:466 / 472
页数:7
相关论文
共 31 条
[11]
Sex differences and similarities in the management and outcome of stroke patients [J].
Holroyd-Leduc, JM ;
Kapral, MK ;
Austin, PC ;
Tu, JV .
STROKE, 2000, 31 (08) :1833-1837
[12]
Predictors of Intracerebral Hemorrhage Severity and Its Outcome in Japanese Stroke Patients [J].
Hosomi, Naohisa ;
Naya, Takayuki ;
Ohkita, Hiroyuki ;
Mukai, Mao ;
Nakamura, Takehiro ;
Ueno, Masaki ;
Dobashi, Hiroaki ;
Murao, Koji ;
Masugata, Hisashi ;
Miki, Takanori ;
Kohno, Masakazu ;
Kobayashi, Shotai ;
Koziol, James A. .
CEREBROVASCULAR DISEASES, 2009, 27 (01) :67-74
[13]
Trends in incidence and outcome of stroke in Perth, Western Australia during 1989 to 2001 - The Perth Community Stroke Study [J].
Islam, Md Shaheenul ;
Anderson, Craig S. ;
Hankey, Graeme J. ;
Hardie, Kate ;
Carter, Kristie ;
Broadhurst, Robyn ;
Jamrozik, Konrad .
STROKE, 2008, 39 (03) :776-782
[14]
Imaging and clinical prognostic indicators for early hematoma enlargement after spontaneous intracerebral hemorrhage [J].
Ji, Nan ;
Lu, Jing Jing ;
Zhao, Yuan Li ;
Wang, Shuo ;
Zhao, Ji Zong .
NEUROLOGICAL RESEARCH, 2009, 31 (04) :362-366
[15]
Incidence and trends of stroke and its subtypes in China - Results from three large cities [J].
Jiang, B ;
Wang, WZ ;
Chen, HL ;
Hong, Z ;
Yang, QD ;
Wu, SP ;
Du, XL ;
Bao, QJ .
STROKE, 2006, 37 (01) :63-68
[16]
Spontaneous Intracerebral Hemorrhage: Management [J].
Kim, Jun Yup ;
Bae, Hee-Joon .
JOURNAL OF STROKE, 2017, 19 (01) :28-39
[17]
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association [J].
Morgenstern, Lewis B. ;
Hemphill, J. Claude, III ;
Anderson, Craig ;
Becker, Kyra ;
Broderick, Joseph P. ;
Connolly, E. Sander, Jr. ;
Greenberg, Steven M. ;
Huang, James N. ;
Macdonald, R. Loch ;
Messe, Steven R. ;
Mitchell, Pamela H. ;
Selim, Magdy ;
Tamargo, Rafael J. .
STROKE, 2010, 41 (09) :2108-2129
[18]
Sex-related time-dependent variations in post-stroke survival-evidence of a female stroke survival advantage [J].
Olsen, Tom Skyhoj ;
Dehlendorff, Christian ;
Andersen, Klaus Kaae .
NEUROEPIDEMIOLOGY, 2007, 29 (3-4) :218-225
[19]
Regional differences in incidence rates, outcome predictors and survival of stroke [J].
Ováry, C ;
Suzuki, K ;
Nagy, Z .
NEUROEPIDEMIOLOGY, 2004, 23 (05) :240-246
[20]
Ricardo AH, 2002, NEUROL RES, V24, pS58