Antigen-specific immune function after hematopoietic stem cell transplantation

被引：4

作者：

Parkman, R

机构：

[1] Childrens Hosp Los Angeles, Div Res Immunol Bone Marrow Transplant, Los Angeles, CA 90027 USA

[2] Univ So Calif, Keck Sch Med, Dept Pediat, Los Angeles, CA 90027 USA

来源：

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | 2003年 / 9卷 / 05期

关键词：

thymopoiesis; T-cell excision circle; antigen-specific function; graft-versus-host disease; immunodeficiency;

D O I：

10.1016/S1083-8791(03)00086-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hematopoietic stem cell recipients are characterized by an immunodeficiency of varying severity and duration. The present review focuses on the antigen-specific function of recipients with the hypothesis that die acquisition of antigen-specific function is predictive of the recipient's capacity to resist lethal infection with environmental pathogens. (C) 2003 American Society for Blood and Marrow Transplantation.

引用

收藏

页码：287 / 291

页数：5

相关论文

共 36 条

[1]

ATKINSON K, 1979, BLOOD, V53, P720

[2]

ATKINSON K, 1986, BONE MARROW TRANSPL, V1, P121

[3] PHENOTYPE OF RECOVERING LYMPHOID-CELL POPULATIONS AFTER MARROW TRANSPLANTATION [J].

AULT, KA ;

ANTIN, JH ;

GINSBURG, D ;

ORKIN, SH ;

RAPPEPORT, JM ;

KEOHAN, ML ;

MARTIN, P ;

SMITH, BR .

JOURNAL OF EXPERIMENTAL MEDICINE, 1985, 161 (06) :1483-1502

[4]

Bhushan V, 2002, BLOOD, V100, p851A

[5] Changes in thymic function with age and during the treatment of HIV infection [J].

Douek, DC ;

McFarland, RD ;

Keiser, PH ;

Gage, EA ;

Massey, JM ;

Haynes, BF ;

Polis, MA ;

Haase, AT ;

Feinberg, MB ;

Sullivan, JL ;

Jamieson, BD ;

Zack, JA ;

Picker, LJ ;

Koup, RA .

NATURE, 1998, 396 (6712) :690-695

[6] Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution [J].

Douek, DC ;

Vescio, RA ;

Betts, MR ;

Brenchley, JM ;

Hill, BJ ;

Zhang, L ;

Berenson, JR ;

Collins, RH ;

Koup, RA .

LANCET, 2000, 355 (9218) :1875-1881

[7]

FORMAN SJ, 1982, TRANSPLANTATION, V34, P96

[8] Cytomegalovirus-specific CD4+ and CD8+ T-cells follow a similar reconstitution pattern after allogeneic stem cell transplantation [J].

Foster, AE ;

Gottlieb, DJ ;

Sartor, M ;

Hertzberg, MS ;

Bradstock, KF .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2002, 8 (09) :501-511

[9] Antibody responses to vaccinations given within the first two years after transplant are similar between autologous peripheral blood stem cell and bone marrow transplant recipients [J].

Gandhi, MK ;

Egner, W ;

Sizer, L ;

Inman, I ;

Zambon, M ;

Craig, JIO ;

Marcus, RE .

BONE MARROW TRANSPLANTATION, 2001, 28 (08) :775-781

[10] CELLULAR-IMMUNITY TO VACCINATIONS AND HERPESVIRUS INFECTIONS AFTER BONE-MARROW TRANSPLANTATION [J].

GRATAMA, JW ;

VERDONCK, LF ;

VANDERLINDEN, JA ;

VANHEUGTEN, JG ;

KREEFT, HAJG ;

DAMARO, J ;

ZWAAN, FE ;

DEGAST, GC .

TRANSPLANTATION, 1986, 41 (06) :719-724

← 1 2 3 4 →