Antigen-specific immune function after hematopoietic stem cell transplantation

被引:4
作者
Parkman, R
机构
[1] Childrens Hosp Los Angeles, Div Res Immunol Bone Marrow Transplant, Los Angeles, CA 90027 USA
[2] Univ So Calif, Keck Sch Med, Dept Pediat, Los Angeles, CA 90027 USA
关键词
thymopoiesis; T-cell excision circle; antigen-specific function; graft-versus-host disease; immunodeficiency;
D O I
10.1016/S1083-8791(03)00086-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hematopoietic stem cell recipients are characterized by an immunodeficiency of varying severity and duration. The present review focuses on the antigen-specific function of recipients with the hypothesis that die acquisition of antigen-specific function is predictive of the recipient's capacity to resist lethal infection with environmental pathogens. (C) 2003 American Society for Blood and Marrow Transplantation.
引用
收藏
页码:287 / 291
页数:5
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