This paper presents an examination of the effects of high labour turnover in a serial assembly environment. The effect of personnel turnover on the throughput of a serial assembly line is investigated along with the active rules at management's disposal to ameliorate this effect. The development and the results of the simulation models used to investigate the problem are presented. Results show that the impact of high turnover on throughput is significant and that some of the active rules introduced in this paper have a significant effect on its reduction.